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Upstream Biomanufacturing (BTEC) Coursework 

BEC 563 - Fermentation of Recombinant Microorganisms

Performed 2-liter bioreactor fermentation to obtain heterologous expression of scFv13R4, a recombinant antibody fragment protein, in Escherichia coli

BEC 526 - Upstream Biomanufacturing Laboratory

Operated a 30-litre bioreactor in batch and fed-batch modes for heterologous expression of Green Fluorescent Protein in Escherichia coli, and applied sterilization practices with yield considerations and Bioprocessing equipment guidelines

BEC 580 - cGMP Fermentation Operations

Learned about the application of microbial fermentation techniques at production scale and evaluation of the issues inherent in the integration of microbial fermentation unit operations, scale-up/production, and current Good Manufacturing Practice (cGMP) compliance.

BEC 575 - Global Regulatory Affairs for Medical Products

Studied quality systems used to meet the regulatory requirements for developing, testing, manufacturing, and selling medical products in the global marketplace. Gained knowledge about the Regulatory Affairs/ Quality Assurance Department within a pharmaceutical, biomanufacturing and medical device industry.

BEC 577 - Advanced Biomanufacturing and Biocatalysis

Overview of biomanufacturing using microorganisms (bacteria, yeast, fungi) and eukaryotic systems (hybridomas, insect, plant, CHO cells), with a focus on industrial methods. Covers process design for optimizing heterologous protein expression, cell line and metabolic engineering, protein and pathway engineering, and production of biotherapeutics, vaccines, enzymes, and diagnostics.

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